| | | Saturday, May 1st, 2021 | | Signed SP Víctor Rodríguez to a 3-year contract extension worth a total of $5,400,000. |
| Friday, April 30th, 2021 | | Signed SP Santiago Rodríguez to a minor league contract extension. |
| Tuesday, April 27th, 2021 | | Signed free agent SP Dragisa Cvijic to a minor league contract. |
| Tuesday, April 20th, 2021 | | Signed free agent 3B Antonio Mendez to a minor league contract. | | Signed free agent 1B Wakie Njowga to a minor league contract. | | Signed free agent SP Santiago Rodríguez to a minor league contract. | | Signed free agent MR Anthony Bouman to a minor league contract. | | Signed free agent SP Jeff Rogers to a minor league contract. | | Signed free agent SP Cedric Seals to a minor league contract. |
| Monday, April 19th, 2021 | | 3B Daniel Morán was designated for assignment and placed on waivers. | | SS Javier Paredes was designated for assignment and placed on waivers. | | Purchased the contract of 1B Júlio Rencurel from Triple A Peoria. | | Promoted SP Enrique Vega from Double A Moline to Triple A Peoria. | | Promoted SP Gustavo Díaz from Double A Moline to Triple A Peoria. | | Promoted 2B Jonathan Brown from Double A Moline to Triple A Peoria. | | Promoted MR Danny Hayes from Single A Pekin to Double A Moline. | | Promoted SP Alec Walker from Single A Pekin to Double A Moline. | | Promoted 1B Pedro Ruíz from Single A Pekin to Double A Moline. | | Traded 24-year-old reliever Ray Childs to the New York Gothams, getting 17-year-old minor league reliever Manny Hunt, 22-year-old minor league third baseman Jack Bryant and a 2nd round draft pick in return. | | Traded 28-year-old reliever Orlando Maldonado to the Alaska Freeze, getting 21-year-old minor league catcher Alfonso Casas in return. | | Traded 26-year-old third baseman Daniel Morán to the Los Angeles Natives, getting 24-year-old minor league shortstop Kenny Baumgartner, 21-year-old starting pitcher Chandler Morgan, 18-year-old minor league first baseman José Ortíz and 19-year-old minor league closer Mark Taylor in return. | | Traded 27-year-old shortstop Javier Paredes to the Los Angeles Natives, getting 18-year-old minor league starting pitcher Ivan Mansfield, a 1st round draft pick and a 2nd round draft pick in return. | | Placed SS Kenny Baumgartner on the 40-man roster. | | Placed SS Kenny Baumgartner on the active roster. |
| Monday, March 1st, 2021 | | Drafted LF Pablo Ruíz in the 2021 first-year player draft (Round 1, Pick 11, 11th overall pick). | | Drafted SP Tracy Martin in the 2021 first-year player draft (Round 1, Pick 13, 13th overall pick). | | Drafted 3B Jeff Parker in the 2021 first-year player draft (Round 1, Pick 15, 15th overall pick). | | Drafted C Terry Faulkner in the 2021 first-year player draft (Round 1, Pick 22, 22nd overall pick). | | Drafted 2B Domingo Valdés in the 2021 first-year player draft (Round 2, Pick 7, 39th overall pick). | | Drafted MR Jeremy Roberson in the 2021 first-year player draft (Round 2, Pick 8, 40th overall pick). | | Drafted 3B Jerry Moore in the 2021 first-year player draft (Round 2, Pick 14, 46th overall pick). | | Drafted C Franco Guzmán in the 2021 first-year player draft (Round 2, Pick 20, 52nd overall pick). | | Drafted 2B Jason Dickinson in the 2021 first-year player draft (Round 2, Pick 23, 55th overall pick). | | Drafted C Alfonso Casas in the 2021 first-year player draft (Round 3, Pick 1, 65th overall pick). | | Drafted MR Alec Walker in the 2021 first-year player draft (Round 3, Pick 9, 73rd overall pick). | | Drafted MR Ángel Morales in the 2021 first-year player draft (Round 3, Pick 10, 74th overall pick). | | Drafted 2B Chris Hennessey in the 2021 first-year player draft (Round 3, Pick 12, 76th overall pick). | | Drafted CF John Kelley in the 2021 first-year player draft (Round 4, Pick 5, 102nd overall pick). | | Drafted SP Keith Fraser in the 2021 first-year player draft (Round 4, Pick 8, 105th overall pick). | | Drafted SP Ken Phillips in the 2021 first-year player draft (Round 4, Pick 23, 120th overall pick). | | Drafted MR Jon Green in the 2021 first-year player draft (Round 4, Pick 29, 126th overall pick). | | Drafted 1B Bill Thomas in the 2021 first-year player draft (Round 5, Pick 5, 136th overall pick). | | Drafted MR Charles Lacy in the 2021 first-year player draft (Round 5, Pick 14, 145th overall pick). | | Drafted CF Juan McNeill in the 2021 first-year player draft (Round 6, Pick 5, 177th overall pick). | | Drafted CF Cristián Alea in the 2021 first-year player draft (Round 7, Pick 5, 212nd overall pick). | | Drafted MR Ted Whitaker in the 2021 first-year player draft (Round 8, Pick 5, 236th overall pick). | | Drafted 2B Ramón Sánchez in the 2021 first-year player draft (Round 9, Pick 5, 260th overall pick). | | Drafted SP Dennis Joyce in the 2021 first-year player draft (Round 10, Pick 5, 284th overall pick). |
| Sunday, November 22nd, 2020 | | MR Juan Valle received a 1-year contract through arbitration worth a total of $1,500,000. | | MR Ray Childs received a 1-year contract through arbitration worth a total of $600,000. | | MR Michael Austin received a 1-year contract through arbitration worth a total of $875,000. | | SP Víctor Rodríguez received a 1-year contract through arbitration worth a total of $1,700,000. | | MR Kozue Nakamura becomes a free-agent. | | 1B Michizane Kichida received a 1-year contract through arbitration worth a total of $3,710,000. | | SS Javier Paredes received a 1-year contract through arbitration worth a total of $9,000,000. | | 3B Daniel Morán received a 1-year contract through arbitration worth a total of $10,000,000. |
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