| Monday, March 1st, 2021 |
| Drafted MR Coy Lee in the 2021 first-year player draft (Round 1, Pick 18, 18th overall pick). |
| Drafted SP Leonard Watson in the 2021 first-year player draft (Round 2, Pick 1, 33rd overall pick). |
| Drafted CF Edward Kellogg in the 2021 first-year player draft (Round 6, Pick 14, 186th overall pick). |
| Drafted MR Steve Richardson in the 2021 first-year player draft (Round 7, Pick 14, 221st overall pick). |
| Drafted RF Augusto Sáenz in the 2021 first-year player draft (Round 8, Pick 14, 245th overall pick). |
| Drafted 1B Kenneth Puckett in the 2021 first-year player draft (Round 9, Pick 14, 269th overall pick). |
| Drafted CF Júlio Zavala in the 2021 first-year player draft (Round 10, Pick 14, 293rd overall pick). |
| Wednesday, November 25th, 2020 |
| 3B Wyatt Peterson received a 1-year contract through automatic renewal worth a total of $400,000. |
| MR Travis Miller received a 1-year contract through automatic renewal worth a total of $400,000. |
| CF Mike Childress received a 1-year contract through automatic renewal worth a total of $400,000. |
| 2B Roy Ross received a 1-year contract through automatic renewal worth a total of $400,000. |
| C Jorge Salazar received a 1-year contract through automatic renewal worth a total of $400,000. |
| CF Miguel Areizaga received a 1-year contract through automatic renewal worth a total of $400,000. |
| RF Jesús Rocha becomes a free-agent. |
| LF Zachary Jenkins received a 1-year contract through automatic renewal worth a total of $400,000. |
| CF António Gómez received a 1-year contract through automatic renewal worth a total of $400,000. |
| SP Avery Roark received a 1-year contract through automatic renewal worth a total of $400,000. |
| SP Chip Brown becomes a free-agent. |
| C Cisco Batista becomes a free-agent. |
| LF Joey Franklin received a 1-year contract through automatic renewal worth a total of $400,000. |
| SS Kevin George becomes a free-agent. |
| SP Michael Collins becomes a free-agent. |
| C Nobuyoshi Hamada received a 1-year contract through automatic renewal worth a total of $400,000. |
| SP António Andrade becomes a free-agent. |
| SP Artie Walker becomes a free-agent. |
| SP Bob Williams becomes a free-agent. |
| SP Bob Phillips becomes a free-agent. |
| MR Frank Martin becomes a free-agent. |
| C Eric Gross becomes a free-agent. |
| C Lane Ellis becomes a free-agent. |
| RF Clarence Sims becomes a free-agent. |
| RF Ignacio García becomes a free-agent. |
| CF Sam Turner becomes a free-agent. |
| RF Matt Arnold becomes a free-agent. |
| 1B Augusto Valdés becomes a free-agent. |
| 1B Hayden Cypert becomes a free-agent. |
| 2B Jack Hankins becomes a free-agent. |
| SP Livio Fittipaldi becomes a free-agent. |
| MR Ray Stevens becomes a free-agent. |
| MR Anthony Bouman becomes a free-agent. |
| 3B Eddie Hurt becomes a free-agent. |
| LF Luis Gutiérrez becomes a free-agent. |
| LF Ramón Pinto becomes a free-agent. |
| 3B Salvador Vásquez becomes a free-agent. |
| Sunday, November 22nd, 2020 |
| SS Nate Grant received a 1-year contract through arbitration worth a total of $3,172,500. |
| MR Fernando Gonzáles received a 1-year contract through arbitration worth a total of $600,000. |
| 1B Kelly Waters received a 1-year contract through arbitration worth a total of $2,431,000. |
| MR Dan Watts received a 1-year contract through arbitration worth a total of $2,100,000. |